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Make sure that your Outlook client is updated with all service packs and also remove all Add-ins. It should fix the issue.
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does anyone have the hot fix number?<br />
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Hotfix:935411<br />
<a href="http://support.microsoft.com/kb/935411" rel="ugc nofollow">http://support.microsoft.com/kb/935411</a><br />
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The download link is near the top of the page. I just applied it for a user I had who was experiencing this issue and it resolved her problems.<br />

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When the orhanizer of a meeting request tries to modify a meeting request a message displays the following: The Item could not be saved because it has been modified by another user or in another window.<br />
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When the orhanizer of a meeting request tries to modify a meeting request a message displays the following: The Item could not be saved because it has been modified by another user or in another window.




Outlook Meeting requests -  cannot update or modify

Exchange is the server side of a collaborative application product that is part of the Microsoft Server infrastructure. Exchange's major features include email, calendaring, contacts and tasks, support for mobile and web-based access to information, and support for data storage.

Exchange

Microsoft Outlook is a personal information manager from Microsoft, available as a part of the Microsoft Office suite. Although often used mainly as an email application, it also includes a calendar, task manager, contact manager, note-taker, journal, and web browser.