Exchange Licensing and Security

II have the pleasure of configuring Exchange 2007 for a company that has approximately 100 users.  I would like to know what I need in regards to licensing for Exchange 2007 Enterprise for use on an existing VMWare ESX Server 3.5.  Since I can load any operating system would you chose 2003 R2 or 2008?  We are currently using 2008 for our Domain Controller and the current domain function level is Windows 2000 native.   I would also like to know what the recommended memory allocation would be for this many users and approximate hard disk space.  Also what type of anti-virus and spam filtering applications would you recommend.  Normally I would use MX Logic for the anti-virus and filtering but the costs would be too much on a monthly basis.  
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tigermattConnect With a Mentor Commented:

I would most definitely recommend that you go with Windows Server 2008 (x64 edition, remember). In my experience with it so far, it has proven to be incredibly reliable. The instructions for installing Exchange 2007 to Server 2008 can be found at The most important thing is to remember you must install the Exchange 2007 SP1 software; Server 2008 will not support any version of Exchange prior to this version.

The minimum RAM requirement for Exchange 2007 is 2GB. I would probably say to double this and see how it goes with your users. You can always add more in future if necessary. As for hard disk space requirements, it's difficult to say: it depends on many factors, such as how heavy your users are, how tidy they keep their mailboxes etc. If you impose quotas on their mailboxes though, and use Exchange's features to clear folders such as Deleted Items automatically after a set number of days, you may be able to help manage their mailbox size though.

The most appropriate anti-virus for Exchange is going to be MS Forefront. It is an MS security product which is designed to work with Exchange 2007, and obviously integrates with it very well. My second option would be AVG's (Grisoft) Email Server Edition.

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