IIS 6.0 Application Pools Hang at Random Intervals

I have a website that fails at random intervals. The development team thinks that issue is with the application pool hanging but everytime the site stops responding the app pool seems to be running and I get the following error in the event logs. The server is Windows 2003 SP2 running on VMWare ESX3.5 server attached to an EMC NS20 SAN. The server is up to date on patches. The SQL server is the same config running SQL 2000. Any insight would be greatly appreciated.

Event code: 3005
Event message: An unhandled exception has occurred.
Event time: 10/7/2008 8:58:46 AM
Event time (UTC): 10/7/2008 12:58:46 PM
Event ID: 291e327915c34c58a96d4be3002ddc09
Event sequence: 25
Event occurrence: 1
Event detail code: 0
 
Application information:
    Application domain: /LM/W3SVC/1071726003/ROOT-1-128678578159037282
    Trust level: Full
    Application Virtual Path: /
    Application Path: D:\inetpub\wwwroot\www.corp.com\
    Machine name: VP-WWW
 
Process information:
    Process ID: 4768
    Process name: w3wp.exe
    Account name: NT AUTHORITY\NETWORK SERVICE
 
Exception information:
    Exception type: InvalidOperationException
    Exception message: There is already an open DataReader associated with this Command which must be closed first.
 
Request information:
    Request URL: http://xxx.corp.com/showPage2Col.aspx?redir=sites 
    Request path: /showPage2Col.aspx
    User host address: xxx.29.1.16
    User:  
    Is authenticated: False
    Authentication Type:  
    Thread account name: NT AUTHORITY\NETWORK SERVICE
 
Thread information:
    Thread ID: 6
    Thread account name: NT AUTHORITY\NETWORK SERVICE
    Is impersonating: False
    Stack trace:    at System.Data.SqlClient.SqlInternalConnectionTds.ValidateConnectionForExecute(SqlCommand command)
   at System.Data.SqlClient.SqlConnection.ValidateConnectionForExecute(String method, SqlCommand command)
   at System.Data.SqlClient.SqlCommand.ValidateCommand(String method, Boolean async)
   at System.Data.SqlClient.SqlCommand.RunExecuteReader(CommandBehavior cmdBehavior, RunBehavior runBehavior, Boolean returnStream, String method, DbAsyncResult result)
   at System.Data.SqlClient.SqlCommand.RunExecuteReader(CommandBehavior cmdBehavior, RunBehavior runBehavior, Boolean returnStream, String method)
   at System.Data.SqlClient.SqlCommand.ExecuteReader(CommandBehavior behavior, String method)
   at System.Data.SqlClient.SqlCommand.ExecuteDbDataReader(CommandBehavior behavior)
   at System.Data.Common.DbCommand.System.Data.IDbCommand.ExecuteReader(CommandBehavior behavior)
   at System.Data.Common.DbDataAdapter.FillInternal(DataSet dataset, DataTable[] datatables, Int32 startRecord, Int32 maxRecords, String srcTable, IDbCommand command, CommandBehavior behavior)
   at System.Data.Common.DbDataAdapter.Fill(DataTable[] dataTables, Int32 startRecord, Int32 maxRecords, IDbCommand command, CommandBehavior behavior)
   at System.Data.Common.DbDataAdapter.Fill(DataTable dataTable)
   at clsModFunctions.ExecuteSQL(String sSQL, Boolean OptIsDev) in http://server//App_Code/clsModFunctions.vb:line 58
   at userControls_uc2Col.Page_Load(Object sender, EventArgs e) in http://server//userControls/uc2Col.ascx.vb:line 18
   at System.Web.UI.Control.OnLoad(EventArgs e)
   at System.Web.UI.Control.LoadRecursive()
   at System.Web.UI.Control.LoadRecursive()
   at System.Web.UI.Control.LoadRecursive()
   at System.Web.UI.Page.ProcessRequestMain(Boolean includeStagesBeforeAsyncPoint, Boolean includeStagesAfterAsyncPoint)