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RPC over HTTP stops working over time

We've got a weird situation happening on a backend Exchange cluster. Here is a our Current setup:

Front end in DMZ
2 backend clusters Cluster01, Cluster02 behind firewall
Cluster01 has 4 nodes Node A and B are a pair and Node C and D are a pair

The active node of Cluster01 pair C and D Intermittently loses the ability for RPC over HTTP but a fail over fixes the issue. Those same users can still use OWA. Users on Cluster01 A and B pair have no problem nor does Cluster02 with rpc over http during the same time that cluster01 pair C and D are having problems. So it's narrowed down to node pair C and D but I'm not sure where to go at this point.
1 Solution
Please look over my blog on Outlook Anywhere I know its related to EX 2007 however from Ex 2003 sp2 there want not any change in the way it works.


It will walk you through some troubleshooting with rpc diag,

basically the mbx server makes referals to its self and calls to DC/gc's so it could be any number of issues.

You also stated a failover fixes this, if you fail back to the affect nodes does it work again?

have you checked the event logs, have you checked to a memory leak etc?
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