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In your account definition in Outlook, what do you have as your outgoing (SMTP) server ? <br />
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The following page from Comcast tells you how to configure your Outlook mail client to retrieve and send email with their service:<br />
<a href="http://www.comcast.com/customers/faq/FaqDetails.ashx?ID=2299&fss=outlook" rel="ugc">http://www.comcast.com/customers/faq/FaqDetails.ashx?ID=2299&fss=outlook</a><br />
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Hope this helps,<br />
Christophe
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In your account definition in Outlook, what do you have as your outgoing (SMTP) server ?

The following page from Comcast tells you how to configure your Outlook mail client to retrieve and send email with their service:
http://www.comcast.com/customers/faq/FaqDetails.ashx?ID=2299&fss=outlook [http://www.comcast.com/customers/faq/FaqDetails.ashx?ID=2299&fss=outlook]


Hope this helps,
Christophe

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The Comcast FAQ page you refer to is for use when traveling away from high-speed internet. My SMTP is set as it should be.
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The Comcast FAQ page you refer to is for use when traveling away from high-speed internet. My SMTP is set as it should be.

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I contacted Comcast and was informed the SMTP default had been changed from 25 to 587. In making this change, my problem was solved.
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I contacted Comcast and was informed the SMTP default had been changed from 25 to 587. In making this change, my problem was solved.

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I currently can receive e-mail on my pop.comcast.net account. Until recently I could send e-mail on this account as well. What should I do to correct this and restore my ability to send e-mail? 
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I currently can receive e-mail on my pop.comcast.net account. Until recently I could send e-mail on this account as well. What should I do to correct this and restore my ability to send e-mail? 

Outlook is unable to connect to your outgoing (SMTP) e-mail server. (0x80042109)

Interactions between email servers and clients are governed by email protocols. The three most common email protocols are POP, IMAP and MAPI. Most email software operates under one of these (and many products support more than one).  The correct protocol must be selected, and correctly configured, if you want your email account to work.

Email Protocols

Office Productivity refers both to the act of being productive and efficient in an office or professional environment, as well as the software applications used to "produce" information. This includes the development of professional skills, creating work processes, and almost any program used to create or modify a document, image, audio or video clip. However, business application suites such as Microsoft Office, which include word processing, spreadsheet and presentation programs, are typically called productivity software, as contrasted with a "utility program," such as a file manager, which is used to organize files and folders on the computer. Many office- and business-oriented groups of programs are organized into suites.

Office Productivity

Within Internet message handling services (MHS), a message transfer agent or mail transfer agent (MTA) or mail relay is software that transfers electronic mail messages from one computer to another using a client–server application architecture. A MTA implements both the client (sending) and server (receiving) portions of the Simple Mail Transfer Protocol (SMTP). The terms mail server, mail exchanger, and MX host may also refer to a computer performing the MTA function. The Domain Name System (DNS) associates a mail server to a domain with mail exchanger (MX) resource records containing the domain name of a host providing MTA services.