I get this error in Outlook 2003: 0x80042109. Then I setup the account in Thunderbird and got this message:
"The message could not be sent because connecting to SMTP server server name failed. The server may be unavailable or is refusing SMTP connections. Please verify that your SMTP server setting is correct and try again, or else contact your network administrator."
I have setup a different account in Outlook but since it won't connect through Thunderbird my assumption is that it is in the O/S.
Windows XP Media Center Edition
Intel P4 2.8GHz