The OS is fully patched.
Logging in with Domain Admin account
DEP is turned to lowest setting (essential Windows processes only)
Nothing of note in any of the logs
DNS entries look good
Deleted and recreated profiles
nltest reports secure channel is good
Firewall, antivirus disabled for testing
There were no issues setting up the server that I'm aware of (it was a multi-shift project), but now that the server is fully installed and patched I'm unable to run any exe's. If the .exe is on another machine I'm able to browse to it, but attempting to execute an installer gets an error:
"Windows cannot access the specified device, path of file. You may not have appropriate permissions to access the item."
The "item" exists, and I can run it when logged into another server. If the exe is local the same error occurs. Two other domain admins have had the same result.
I'm out of ideas. Anyone?