"If {AdoConnection} IsNot Nothing Then" vs "If Not {AdoConnection} Is Nothing Then"

Is one better to use than the other?  Is there another way of checking if something (in this case, an ADO Connection object) is nothing.

In VB6, I would write:

If Not {AdoConnection} Is Nothing Then
End If

In VB.NET, neither the above nor the following generate an error:

If {AdoConnection} IsNot Nothing Then
End If

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Guy Hengel [angelIII / a3]Billing EngineerCommented:
what about
If Not IsNothing({AdoConnection}) Then
End If

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CarlaGibsonAuthor Commented:
Does it matter which way is used?  They all give the same results.  Is it just personal preference or is there a reason to use one over the other?
Guy Hengel [angelIII / a3]Billing EngineerCommented:
> They all give the same results.
the only difference could then be performance, right?!

in which case, IsNothing is a function call, which will have a slight overhead over the other methods.

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