ASPNET AJAX Fails to load on Page Refresh

schmidlop used Ask the Experts™
I am using ASPNET AJAX, VS2008, Framework 3.5. I have ASPNET AJAX working fine in many places. I have a page which has several AJAX controls on it all of which work fine, except when the page is refreshed (via F5) it gives the infamous 'ASP.NET Ajax client-side framework failed to load'. The usual fix doesn't work because I already have AJAX working its not a web.config issue. I'm stumped any ideas would be welcome.
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Maybe you want to see if any suggestion at this site would help you. 
Turns out that Vista (IIS 7) was the cause of the problem this blog was what helped me solve the problem

I was missing this:

<add name="ScriptResource" preCondition="integratedMode"  
verb="GET,HEAD" path="ScriptResource.axd"  
type="System.Web.Handlers.ScriptResourceHandler, System.Web.Extensions, Version=, Culture=neutral, PublicKeyToken=31BF3856AD364E35" />    


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