troubleshooting Question

There was a SMTP communication problem with the recipient's email server. Please contact your system administrator. <mail.SERVER.com #5.5.0 smtp;550 sorry, mailbox

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mbaker100196Flag for United States of America asked on
ExchangeEmail Protocols
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When one of my users tries to send an email to a specific address, he gets this error message:

            There was a SMTP communication problem with the recipient's email server.  Please contact your system administrator.
            <ouremailserver.com #5.5.0 smtp;550 sorry, mailbox unavailable (#5.5.0)>
 
I have tried to telnet to the destination smtp server and get the same error when I tried to manually send and email the the specific address
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