<div>
I have opened the case with MS
</div>


<div>
<div class="content wysiwyg-content">
The new installation of Exchange 2007 OWA on windows 2008.worked for one month. Now, it doesn't work. When try to access it, we receive this message:<br />
Server Error in Application &quot;DEFAULT WEB SITE/OWA&quot;<br />
Internet Information Services 7.0<br />
Error Summary <br />
HTTP Error 500.21 - Internal Server Error<br />
Handler &quot;PageHandlerFactory-ISAPI-<wbr />2.0-64&quot; has a bad module &quot;IsapiModule&quot; in its module list<br />
Detailed Error Information <br />
Module &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;IIS Web Core<br />
Notification &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;ExecuteRequestHandler<br />
Handler &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;PageHandlerFactory-ISAPI-2<wbr />.0-64<br />
Error Code &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;0x8007000d<br />

</div>
</div>


The new installation of Exchange 2007 OWA on windows 2008.worked for one month. Now, it doesn't work. When try to access it, we receive this message:
Server Error in Application "DEFAULT WEB SITE/OWA"
Internet Information Services 7.0
Error Summary 
HTTP Error 500.21 - Internal Server Error
Handler "PageHandlerFactory-ISAPI-2.0-64" has a bad module "IsapiModule" in its module list
Detailed Error Information 
Module	IIS Web Core
Notification	ExecuteRequestHandler
Handler	PageHandlerFactory-ISAPI-2.0-64
Error Code	0x8007000d


500 Internet server error on Exchange 2007 OWA

The Windows operating systems have distinct methodologies for designing and implementing networks, and have specific systems to accomplish various networking processes, such as Exchange for email, Sharepoint for shared files and programs, and IIS for delivery of web pages. Microsoft also produces server technologies for networked database use, security and virtualization.

Windows Networking

Exchange is the server side of a collaborative application product that is part of the Microsoft Server infrastructure. Exchange's major features include email, calendaring, contacts and tasks, support for mobile and web-based access to information, and support for data storage.