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Standard connection to iTunes for synchronization is via a USB cable.<br />
<br />
You can also synchronize wirelessly with the Apple MobileMe service (<a href="http://www.me.com" rel="ugc">www.me.com</a>) to syncronize contacts and calendars etc.<br />
<br />
If you need to synchronize a FileMaker database you might want to look at FM Touch (<a href="http://www.fmtouch.com" rel="ugc">www.fmtouch.com</a>)<br />
<br />
Various other apps on the iPhone syncronize data wirelessly (like Evernote and Remember the Milk)
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Standard connection to iTunes for synchronization is via a USB cable.

You can also synchronize wirelessly with the Apple MobileMe service (www.me.com [http://www.me.com]) to syncronize contacts and calendars etc.

If you need to synchronize a FileMaker database you might want to look at FM Touch (www.fmtouch.com [http://www.fmtouch.com])

Various other apps on the iPhone syncronize data wirelessly (like Evernote and Remember the Milk)

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I'm not looking at wireless sync. I'm looking at syncing an app for the iPhone with a computer program database I'm going to build. Is there API or something I can use? Will FMtouch do this?
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I'm not looking at wireless sync. I'm looking at syncing an app for the iPhone with a computer program database I'm going to build. Is there API or something I can use? Will FMtouch do this?

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FmTouch may be the best option. 
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Is it possible to have some type of database on a computer and you can connect your iPhone/iPOD touch to the computer, and the computer and Unit can sync with each other that way, instead of going through Wifi and data connection?
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Is it possible to have some type of database on a computer and you can connect your iPhone/iPOD touch to the computer, and the computer and Unit can sync with each other that way, instead of going through Wifi and data connection?

iPhone or iPOD Touch app sync by USB cable

All of Apple's hardware is produced solely by Apple Inc., who determines internal systems, designs, and prices. Apple buys certain components wholesale from third-party manufacturers. The current Mac product family uses Intel x86-64 processors. All Mac models ship with at least 1 GB RAM as standard. Current Mac computers use ATI Radeon or nVidia GeForce graphics cards and include a dual-function DVD and CD burner, called the SuperDrive. Current Apple hardware includes the iPad, iPhone, iMac, Mac Pro, Macbook, iPod and Apple TV. Discontinued hardware includes the Apple I, Apple II, and the Apple III, the Lisa, the Newton, the Quadra, Performa, Centris, Macintosh II and LC series, the Power Macintosh, iBooks and the MacBook.

Apple Hardware

The iPhone is a smartphone made by Apple Inc. It and the iPad, along with several other mobile devices from Apple, run on the iOS operating system, which has its own topic, as does the iPad for device-specific questions. Native iOS applications are written in Objective-C or in Swift using the Cocoa Touch frameworks or HTML5 compiled with the help of a package manager such as Adobe PhoneGap; a common IDE is Xcode.

iPhone

MySQL is an open source, relational database management system that runs as a server providing multi-user access to a number of databases. Acquired by Oracle in 2009, it is frequently used in combination with PHP installations, powering most of the WordPress installations.