Outbound emails blocked by ASA

Inbound email works along with all internet traffic, but all internal users are unable to send out emails and the queue on my exchange is up over 1,000.  Here is my ASA config

name 204.8.9.42 OWA-External description External IP address of frontmail.greenfieldin.org
name 204.8.9.37 Mail-External description External IP address of antispam.greenfieldin.org
name 10.16.2.3 Mail-Internal description Internal IP address of antispam.greenfieldin.org
name 10.16.2.5 OWA-Internal description Internal IP address of frontmail.greenfieldin.org
!
interface Ethernet0/0
 nameif outside
 security-level 0
 ip address 204.8.9.62 255.255.255.224 standby 204.8.9.61
!
interface Ethernet0/1
 nameif inside
 security-level 100
 ip address 10.16.7.250 255.255.255.0 standby 10.16.7.251
!
interface Ethernet0/2
 nameif DMZ
 security-level 50
 ip address 192.168.51.254 255.255.255.0 standby 192.168.51.253
!
interface Ethernet0/3
 description LAN/STATE Failover Interface
!
interface Management0/0
 shutdown
 nameif management
 security-level 100
 ip address 192.168.1.1 255.255.255.0 standby 192.168.1.2
!
banner login   #############################################################
banner login   #             This device is the property of                #
banner login   #                      City of Greenfield                      #
banner login   # Only authorized users are permited access to this device! #
banner login   #   All activity on this system is monitored and LOGGED.    #
banner login   #        Unauthorized access or activity is PROHIBITED.     #
banner login   #            All violators will be PROSECUTED!              #
banner login   #############################################################
ftp mode passive
clock timezone EST -5
clock summer-time EDT recurring
dns domain-lookup outside
dns domain-lookup inside
dns domain-lookup DMZ
dns server-group DefaultDNS
 domain-name greenfieldin.org
access-list inside_nat0_outbound extended permit ip any 10.16.253.0 255.255.255.248
access-list inside_nat0_outbound extended permit ip any 10.16.253.8 255.255.255.248
access-list Email-Out extended permit tcp any host Mail-Internal eq smtp
access-list Email-Out extended permit tcp any host OWA-Internal eq https
access-list Email-In extended permit tcp any host Mail-External eq smtp
access-list Email-In extended permit tcp any host OWA-External eq https
pager lines 24
logging enable
logging asdm informational
mtu outside 1500
mtu inside 1500
mtu DMZ 1500
mtu management 1500
ip local pool dhcpCOREvpn 10.16.253.1-10.16.253.6 mask 255.255.255.248
ip local pool dhcpUSERSvpn 10.16.253.9-10.16.253.15 mask 255.255.255.248
failover
failover lan unit primary
failover lan interface HeartBeat Ethernet0/3
failover key *****
failover link HeartBeat Ethernet0/3
failover interface ip HeartBeat 10.16.255.1 255.255.255.252 standby 10.16.255.2
no monitor-interface management
icmp unreachable rate-limit 1 burst-size 1
asdm image disk0:/asdm-613.bin
no asdm history enable
arp timeout 14400
global (outside) 1 interface
global (outside) 3 OWA-External netmask 255.255.255.255
global (outside) 2 Mail-External netmask 255.255.255.255
nat (inside) 0 access-list inside_nat0_outbound
nat (inside) 2 Mail-Internal 255.255.255.255
nat (inside) 3 OWA-Internal 255.255.255.255
nat (inside) 1 0.0.0.0 0.0.0.0
static (inside,outside) Mail-External Mail-Internal netmask 255.255.255.255
static (inside,outside) OWA-External OWA-Internal netmask 255.255.255.255
access-group Email-In in interface outside
route outside 0.0.0.0 0.0.0.0 204.8.9.35 1
route inside 10.0.0.0 255.0.0.0 10.16.7.254 1