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Bounced Mail #5.5.0 smtp;552 Unable to process message

A user got the following message today when sending email to one domain. However the messages has arrived to at least 3 of the recipients, which the user confirmed by telephone.

I tried to google it, but only found that 552 means the message was too large, which doesn't seem probable since it has been received.

There was a SMTP communication problem with the recipient's email server.  Please contact your system administrator.

<ourDomain #5.5.0 smtp;552 Unable to process message:

msg.1236927854.923664.5617 - error: recipient: user1@theirDomain failed, reason: Giving up on theirIP. 550 user1@theirDomain... No such user, recipient: user2@theirDomain failed, reason: Giving up on theirIP. 550 user2@theirDomain... No such user, recipient: user3@theirDomain failed, reason: Giving up on theirIP. 550 user3@theirDomain... No such user>
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The colleague that sent the emails said that she had got a message from one of the recipients where the recipient had asked why we had sent the message 4 times (my colleague sent it more then once). Because of that my colleague phoned up the recipients and at least 3 had got the message.

The colleague is out to lunch, but I will double check when she got back that the recipients that received the message are the once that are included in the error message.
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Thanks for the fast response! :)
It's still the remote site that you should look at, your user is sending just fine, the problem relies on the target server, unless he has typed the email address wrong.
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Yeah, that seems more probable the more I read about the error. Told the user to recheck spelling.