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RelindaFlag for United States of America

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How do I turn off port 25 on a Cisco ASA 5510?

We are having an issue at my current job.  Our ISP has reported to us that we have been reported as a Spamming site.  We have had this issue in the past and the way we found out which machine was spamming was by turning off port 25.  The person that turned the port off used software he had in order to do it and of course he took the software with him when he left.  I need to know the commands to turn off port 25 and turn it back on again.  Please help.
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lxtate

I need some help in allowing a computer from my DMZ to see my live network and also to opening port 25 on my ASA 5510 for SMTP traffic.

I have a DMZ 128.x.x.x and my live Network is 192.x.x.x the way this is configured is Live Network is able to see all machines in DMZ but DMZ cant see machines in Live.

Can someone help please this is urgent