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Having multiple nics on the exchange server will only confuse the server and will result in all sorts of bad behaviour. I would advise you to use exchange with just one NIC, unless it is an sbs.<br />
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Rajith.
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Having multiple nics on the exchange server will only confuse the server and will result in all sorts of bad behaviour. I would advise you to use exchange with just one NIC, unless it is an sbs.

Rajith.

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Binding order was correct with the primary NIC first. Removing the gateway resolved the issue - good job.
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Binding order was correct with the primary NIC first. Removing the gateway resolved the issue - good job.

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I have an exchange 2003 server with dual NICS. I would like to dedicate the primary NIC to the Exchange Virtual Server and the 2nd to an iscsi NAS device. When I enable the 2nd NIC w/o File and Print (NAS recommendation) and change the virtual server from &quot;all unassigned&quot; to the primary NIC IP address, outbound mail hangs. When the VS is set to 'all unassigned', mail also hangs, I assume attempting the route mail on the 2nd NIC. How do I configure the virtual server to send and receive mail only on the primary NIC. Currently the NICs are on the same subnet.
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I have an exchange 2003 server with dual NICS. I would like to dedicate the primary NIC to the Exchange Virtual Server and the 2nd to an iscsi NAS device. When I enable the 2nd NIC w/o File and Print (NAS recommendation) and change the virtual server from "all unassigned" to the primary NIC IP address, outbound mail hangs. When the VS is set to 'all unassigned', mail also hangs, I assume attempting the route mail on the 2nd NIC. How do I configure the virtual server to send and receive mail only on the primary NIC. Currently the NICs are on the same subnet.

Binding One IP address to Exchange 2003 Virtual Server

Interactions between email servers and clients are governed by email protocols. The three most common email protocols are POP, IMAP and MAPI. Most email software operates under one of these (and many products support more than one).  The correct protocol must be selected, and correctly configured, if you want your email account to work.

Email Protocols

Exchange is the server side of a collaborative application product that is part of the Microsoft Server infrastructure. Exchange's major features include email, calendaring, contacts and tasks, support for mobile and web-based access to information, and support for data storage.