Publisher-Subscriber + WCF solution for real time appointment scheduler solution

I am looking for the proper architecture for solving the real time appointment scheduler application.  All clients will be connected to the server hosted with SQL Server 2000/2005/2008. Any changes of appointment data, the clients will get the notification from the server. The client will pull/refresh the data for the user interface.

Any article/source code/ recommeded architecture are much appreciated.
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