Mouse connection is lost on Ncomputing X300 randomly

We have a school lab with identical XP Pro pc's all logging in with the same user name and password.  They are in rows of 4 and the machine on the end of the row controls the other 3 with a network Ncard connecting to an Ncomputing x300 box for power, each pc has its monitor, mouse, and keyboard plugged into its own x300 box.  Randomly the mouse will lose connection and not work again on 1 machine and the whole row has to be rebooted by rebooting the controlling computer on the end, which then fixes the problem.  Usually the keyboard and monitor will still respond , while the mouse does not.  Unplugging and reseating the mouse cable to the x300 box does not usually fix it, nor does reseating the network cable in the specific x 300 box.  This happens randomly to different rows at different times and there is no discernible pattern of any certain application being open at the time or any errors.  The whole row then has to be rebooted, causing loss of work and down time.  Has anyone seen this before or had any luck fixing this issue.  We have tried both usb and ps2 mice with similar results and often times a machine will be rebooted to fix it and not lock up the mouse again and work fine for days.
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IndyNCCConnect With a Mentor Author Commented:
They appear to have narrowed it down to happening mostly within one application and they are looking into replacing the application to one that better works with the x300's.  School is out for the summer so they are not as worried about it right now.  I am going to close the question as it appears to be a software issue.
kvm's are not hotplugable thats why you need to reboot all the row
IndyNCCAuthor Commented:
The 3 x300 units are plugged into the computer using rj45 cables into an Ncard.  Were trying to figure out why one mouse out of the row locks up randomly when they are all plugged in the same.  We have also upgraded a few of the machines to XP SP3 and are using different user names on some of them to see if that makes a difference as they were all logging in with the same user name so if they are trying to access something at the same time, it may be locking up trying to connect to the network, not sure.
IndyNCCAuthor Commented:
All 24 machines were logging into the server with the same user name and password, student1, we have now created a user for each pc on the server lab1,lab2, etc and they are now logging into the machines as those so they each have a seperate user name so the same user account is not trying to access the same file, etc at the same time which might cause the freeze.  So far this has kept them from locking up, but the locking up appeared to be random and not every day so we are going to wait before declaring this the solution yet.
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