RPC http wont accept the password

I have RPC-http for Exchange.  It has been working fine for months.  Today, I am no longer able to use RPC for Outlook.  OWA works, windows mobile connects, and over the network are all working. I have not made any changes to Exchange.  

the only  change thar I can think of is that I just set the domain to use NTLMv2 and to disregard other methods of hashing.  Could this cause this issue?
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