Outlook mail gets stuck in outbox and at times will not even go to outbox

My Outlook client will not send all mail when disconnected from Exchange server.  We have 2 accounts setup.  1 is the e-mail, and the other is the exchange account used to backup our laptop users daily.  My user, can send all mail fine, but when disconnected (like when he is at home), he cannot send all mail.  Some mail will say in his outbox, even though he is using his e-mail account and not his exchange account to send.  He can not add contacts without being connected to exchange, and some e-mails will go through spell checker before you send the e-mail, but then it goes back to the e-mail and does not even move it to the outbox.  Clicking send repeatedly yields the same results.  It just sits at the message where you can type, edit, and format the e-mail, but does not move it into the sent or outbox folder when you click send.  It is very wierd.  I am running windows XP SP3 and IE 7 if that makes a difference.  I think there might be a setting the user changed that caused this because he was working fine, then one day this happened about a month agao and he did not notify anyone.
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Manpreet SIngh KhatraSolutions Architect, Project LeadCommented:
What if we use OWA ?
Can you check for the addons in outlook and the AV on the machines ?
No address in cache mode would mean that you have to download OAB ?

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Manpreet SIngh KhatraSolutions Architect, Project LeadCommented:
If the issue is with one user try re-cerating his Outlook profile and check .....
Manpreet SIngh KhatraSolutions Architect, Project LeadCommented:
Any updates on the issue ?
Linktheman2003Author Commented:
What the real issue was with was the Windows PRofile.  I deleted it and recreated it with no issues.
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