MSExchangeTransport / SMTP Protocol / EventID 7004/7010/7002

There's a lot of these daily in the application log of Event Viewer
with Type: Error

My understadning it that these from external sources trying to access our Exchange 2003 servers hosted on SBS 2003 as an open relay. It's been verified many many times with the help of folks at EE and some google pages that my server is not an open relay. Yet these messages keep showing up. Are these telling me of real danger? If not is there a way to get rid of em

This is an SMTP protocol error log for virtual server ID 1, connection #100982. The remote host "213.61.32.35", responded to the SMTP command "rcpt" with "550 #5.1.0 Address rejected AlfredocustodyShelton@gruener-punkt.de  ". The full command sent was "RCPT TO:<AlfredocustodyShelton@gruener-punkt.de>  ".  This will probably cause the connection to fail. 
 
 
 
This is an SMTP protocol error log for virtual server ID 1, connection #100981. The remote host "213.221.60.186", responded to the SMTP command "xexch50" with "500 5.5.1 Unrecognized command  ". The full command sent was "XEXCH50 2304 2  ".  This will probably cause the connection to fail. 
 
This is an SMTP protocol log for virtual server ID 1, connection #100980. The client at "124.11.140.158" sent a "rcpt" command, and the SMTP server responded with "550 5.7.1 Unable to relay for vbibiorm@gmail.com  ". The full command sent was "rcpt TO: <vbibiorm@gmail.com>".  This will probably cause the connection to fail.
 
 
This is an SMTP protocol warning log for virtual server ID 1, connection #100953. The remote host "64.18.6.10", responded to the SMTP command "rcpt" with "451 Can't connect to storopackinc.com - psmtp  ". The full command sent was "RCPT TO:<subtotalphx2@storopackinc.com>  ".  This may cause the connection to fail. 

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