long delay in open files when connected to a network

I'm having troubles on one of our networked PCs. When double-clicking or right-clicking on a network or local file there is an extreme delay before the file opens. This applys to .doc, .xls, .pdf, .htm, etc It doesn't matter what type of file, there is a delay.

However, if I open Word, then do a File > Open, the document opens lickity split. If I unplug the network cable from the computer, I can then double-click or right-click any of the previous documents mentioned (obviously not the ones on the network) and it opens lickity split.

Any suggestions?
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midi152Asked:
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DatedmanCommented:
What kind of Antivirus are you using??  What length delay?  One thing that could be slowing you down is antiviral scanning on open...also could be a NIC issue, what kind of NIC?

Other computers on the network do not have this problem with the same files at the same time?
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midi152Author Commented:
All the computers on the network are Dell Optiplex 740 with integrated NICs.

We have our Symantec EndPoint Protection Enterprise edition managed by a local server with the latest definitions.

There is only one computer reporting the problem listed above.

The delay ranges from 15 seconds to 30 seconds.
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DatedmanCommented:
Might want to try turning off SEP just to eliminate that...
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DatedmanCommented:
Oh and only one reporting the problem doesn't mean that they aren't all experiencing it so best to test with another computer and see if the problem is not specific to the one machine!
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midi152Author Commented:
I've tested on several other machines at our various locations and even on the remote locations on the slowest VLAN, there is no problem. So to me it appears that just this one machine is suffering from the delay while opening.

I disabled SEP and no change.
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DatedmanCommented:
All ip stuff is automatic with DHCP?  If so, next thing might be to disable onboard nic and toss in an extra and see what happens.
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midi152Author Commented:
correct on the dhcp. i tried a new nic with no change. i did upgrade the integrated nic drivers, but no help there....it's almost as if when the computer is plugged into the network, the computer thinks the document or file is somewhere on the network and is having trouble locating it...
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DatedmanCommented:
Very strange.  If IP setup is the same as other computers and the NIC isn't it, I'd check the cable maybe, the HOSTS file, hmmm you know SEP changes take a while to take affect...try making a firewall rule in SEP to allow all traffic on the local subnet just to make sure it isn't filtering stuff regardless?  Also could be the port in the network switch, sheesh I'm grasping at straws here but have actually had that happen, not sure it caused a slowdown tho.
What else is running on this box that isn't running on the others?  Oh you could eliminate all switch/cable stuff by physically swapping two box's locations for a few minutes.
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DatedmanCommented:
Oh and I take it you've checked the event log?
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midi152Author Commented:
Ok, I think I got it working better. I did run a couple of registry cleaners (regscrubxp and glary's registry repair) and removed several items from startup including some services that were not needed. I believe is was a combination of some corrupted registry key and the windows media network sharing. Not for certain, just a guess...thanks for the help and suggestions.
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