Backup Exec. Error, Unable to open \\SBS\Microsoft Information Store\......

I'd suggest running a Windows backup on the Exchange Server: to disk as it's quicker. (Accessories - System Tools - Backup)
This will give you a good idea of whether the problem is on the Exchange server or in Backup Exec.

If you have exchange 2007 and configured continuous replication of database, then you may face this problem

I tried to make a backup of exchange with Ntbackup as carolchi asked.

I get the following error:

Backup Status
Operation: Backup
Active backup destination: File
Media name: "SBS Backup.bkf created 01-07-2009 at 08:55"

Volume shadow copy creation: Attempt 1.
Backup of "SBS\Microsoft Information Store\First Storage Group"
Backup set #1 on media #1
Backup description: "Set created 01-07-2009 at 08:55"
Media name: "SBS Backup.bkf created 01-07-2009 at 08:55"

Backup Type: Normal

Backup started on 01-07-2009 at 08:55.
Backup completed on 01-07-2009 at 10:52.
Directories: 4
Files: 16
Bytes: 20.998.563.684
Time:  1 hour,  57 minutes, and  35 seconds
Backup of "SBS\Microsoft Site Replication Service\SRS Storage"
Backup set #2 on media #1
Backup description: "Set created 01-07-2009 at 08:55"
Media name: "SBS Backup.bkf created 01-07-2009 at 08:55"

Backup Type: Normal

Backup started on 01-07-2009 at 10:53.
The 'Microsoft Site Replication Service' returned 'Error returned from an ESE function call (d).

' from a call to 'HrESEBackupSetup()' additional data '-'The 'Microsoft Site Replication Service' returned 'Functions called in an invalid sequence.

' from a call to 'HrESEBackupClose()' additional data '-'
The operation was ended.
Backup completed on 01-07-2009 at 10:53.
Directories: 0
Files: 0
Bytes: 0
Time:  1 second


Any idea?

https://www.experts-exchange.com/questions/20957069/HrESEBackupSetup-Backup-Error-with-ExSrv-2003.html

Can you explain it in more details, dosent quite understand it. Thx

They were trying to include a Recovery Storage Group in the backup. It is not possible to backup Recovery Storage groups. Did you create a recovery storage group?

Also perhaps try not including the system state in the backup.

I did not create a recovery storage group.

I will try not to include the system state and see what will happend then.

Do also make sure there is no recovery storage group being backed up.
Have you restarted your server?

Theres is no recovery storage group.
No the server has not been restarted?

A restart did the job, Thanks!

Now I got the problem again with the same server, I tried to restart the server but no luck.
Any other idea?
I'll will of cource open another questen if someone gives me the anwser so someone can get the points