How do I create an access list which denies smtp to all nodes except the email server?

How do I create an access list which denies smtp to all nodes except the email server?
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access-list 10 permit tcp host E-Mail Server any eq 25
access-list 10 deny tcp any any
That'll deny a lot more than email, and you can't use a standard acl number, it has to be extended number range.

Assuming that you are applying this to an inbound interface:

access-list 110 permit tcp any host <mail server ip> eq 25
access-list 110 deny tcp any any eq 25
access-list 110 permit ip any any

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