I have one machine that is having this issue. Any Office file, .doc, .xls, .ppt. It takes about 30 seconds for the file to open when double clicked on, either from the network or locally on the desktop. If I open the program first, and access the file, by clicking on open, it works fine. I have tried several things. Uninstall/Re-install, repair, enabling ShellDataCaching. I also intsalled the latest service pack for Office SP3. Still no luck. This is happening under all profiles.