Another odd one here.
I have a client that is now experiencing this problem on a total of three laptops. The issue is that all of the sudden the user can no longer use USB devices - unless they're plugged in at the time off boot, but if they remove the device after Windows has loaded and plug it back in the laptops do not recognize the device. Along with this issue comes Microsoft Office products tend to hang and not respond.
The issues are occurring on two Lenovo ThinkPad T500 laptop and an HP Compaq nx9420. All of the laptops are running Microsoft Windows Vista Business 32-bit. The common software between the devices are Microsoft Office 2007, Symantec EndPoint Protection (now removed from all three systems, and the issue still remains). This issue initially was only on the Compaq laptop. We formatted the system and reinstalled everything from scratch and the system worked for about a month before the issues returned. As I mentioned this is now affecting two other laptops, and seems to be limited to the laptop systems as none of the 50+ desktops have displayed any symptoms.
If anyone could provide me with any suggestions it would be appreciated. I can answer any questions you might have about this issue as well.