Exchange 2007 can not find local Domain Controller


I have the following configuration:
Windows Server SBS 2008 with Exhange 2007.
Every other week I have errors in evenlogs saying exchange can not contact local domain controller OR can not concat Global Catalog... I read somewhere if you re-run setup /prepareAD the issue will get fixed.  Is it safe to re-run this command in a working Exchange 2007 envirnment? YOur input would be greatly appreciated.
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Prep is non-destructive and can be run in a productionsystem during production hours without any issues.


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pete26Author Commented:
Mestha and XCHxpert,

Thank you so much for you fast response. I will run the command shortly and will let you know the result.
pete26Author Commented:
I ran the issues - all is good.
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