OWA receiving 4001 error in I.E.

Cicio1412 used Ask the Experts™
I had to recently reinstall some exchange 2007 files and now the OWA portion is giving this error... "401 - Unauthorized: Access is denied due to invalid credentials.
You do not have permission to view this directory or page using the credentials that you supplied."

This message comes up before you even get to log on, so I am not sure what credentials it is talking about.
Can someone please help ????
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Can you tell the current permission on OWA Virtual directory?
have a look at this link .. should be useful http://support.microsoft.com/kb/907273
Can you find the IIS log entries that show the 401 response?  If you manually replaced some of the files within the owa file heirarchy, there is a good chance that the ACL's aren't the same as the original, which means that Unauthorised Users (which is what your not-yet-logged-in OWA users are) no longer have permission to execute them.

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