Update AD Computer Location and Description from Excel Spreadsheet

I have a delegate account with write access to my OU in our company's AD.  I have an inventory of our computers in Excel specifying the PC name, location and other details.

I would like to write a script to update the location and descriptionfields associated with our computers in the AD. I am unsure how to begin or the best tool.  Should I use VB script, powershell, or something else.

The server is Windows 2003 and client running the script XP.  I am comfortable programming .net etc but would like to use a script so I can make it available for colleagues to use and modify.  Grateful for links with some examples to get me started.