Is there a way to script out gathering the BIOS GUID

If you can find the value it would be via a WMI connection to  the win32_Bios class

Might this do what you need?

http://home.wanadoo.nl/scripting/topics/f12/ultimatebb.cgi-ubb=print_topic;f=12;t=000206.htm

~bp

Does MS store a GUID for the BIOS? Not sure, but there is also the Universal UID and you can get that by running this

wmic CSProduct Get UUID /format:list

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The attached vbscript can poll for the system GUID of the system it's run on.

strComputer = "." 
Set objWMIService = GetObject("winmgmts:\\" & strComputer & "\root\CIMV2") 
Set colItems = objWMIService.ExecQuery( _
    "SELECT * FROM Win32_ComputerSystemProduct",,48) 
For Each objItem in colItems 
    Wscript.Echo "-----------------------------------"
    Wscript.Echo "Win32_ComputerSystemProduct instance"
    Wscript.Echo "-----------------------------------"
    Wscript.Echo "UUID: " & objItem.UUID
Next

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Sorry, mis-typed. That script pulls the UUID from the motherboard, useful if you're using RIS services. I suspect that's what you're after.

Yes this is what i was needing, the UUID is about the same as the GUID. I was once upon a time very familiar with modifying VB, but apparently not now unfortunately.  Therefore, i would like this piped out to  text file with results and is there a way i can pull all of the machines on my Domain from a specific OU.  

I'll need to work on the script some for text output (it's not really tough but $employer expects something productive today), but as far as running it on only a select OU, set it to run as a startup script.

Try this. It writes the UUID to the same directory from which the script is run with the name of the computer it's run on.

strComputer = "." 
Set objWMIService = GetObject("winmgmts:\\" & strComputer & "\root\CIMV2") 
Set colItems = objWMIService.ExecQuery( _
    "SELECT * FROM Win32_ComputerSystem",,48)
' Open file for Writing
Dim fso, MyFile
Set fso = CreateObject("Scripting.FileSystemObject")
For Each objItem in colItems 
	Set MyFile = fso.CreateTextFile(".\" & objItem.Name & "_UUID.txt", True)
Next
' get and write UUID to file
strComputer = "." 
Set objWMIService = GetObject("winmgmts:\\" & strComputer & "\root\CIMV2") 
Set colItems = objWMIService.ExecQuery( _
    "SELECT * FROM Win32_ComputerSystemProduct",,48) 
For Each objItem in colItems
    MyFile.WriteLine "UUID: " & objItem.UUID
Next 
' close the config file
MyFile.Close

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Works great, now let me ask you this, to finish up this question and task.  Is there a way that  this script can pull UUID from LDAP from all systems in Active Directory.