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is BackSpace casuing a postback?<br />
and after postback are you trying to update db?<br />
<br />
can you please post related html and aspx code...
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is BackSpace casuing a postback?
and after postback are you trying to update db?

can you please post related html and aspx code...

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I'm using VB.NET and Winform. Not ASP. 
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do you have any event on keypress? maybe keydown or keyup? or change event?<br />
check those, maybe there is a code running and causing this issue...
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do you have any event on keypress? maybe keydown or keyup? or change event?
check those, maybe there is a code running and causing this issue...

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No Event on Keydown or Keyup.<br />
I don't believe its' code causing this but some how cause it is bound to a &nbsp;numberic field it does not like the backspace ...
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No Event on Keydown or Keyup.
I don't believe its' code causing this but some how cause it is bound to a  numberic field it does not like the backspace ...

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You hit it right on!<br />
That was the problem. DefaultCellStyle.NullValue<wbr />.<br />
Thanks!
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You hit it right on!
That was the problem. DefaultCellStyle.NullValue.
Thanks!

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<div class="content wysiwyg-content">
Using the DataGridView, Bound, on a numeric column when backspacing getting an error:<br />
&nbsp;&quot;Input String was not in a correct format&quot;. How can I prevent this error? Or at least rever from it? 
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Using the DataGridView, Bound, on a numeric column when backspacing getting an error:
 "Input String was not in a correct format". How can I prevent this error? Or at least rever from it? 

DataGridView DataError ?

The .NET Framework is not specific to any one programming language; rather, it includes a library of functions that allows developers to rapidly build applications. Several supported languages include C#, VB.NET, C++ or ASP.NET.

.NET Programming

Visual Basic .NET (VB.NET) is an object-oriented programming language implemented on the .NET framework, but also supported on other platforms such as Mono and Silverlight. Microsoft launched VB.NET as the successor to the Visual Basic language. Though it is similar in syntax to  Visual Basic pre-2002, it is not the same technology,