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You should have mentioned your source: <a href="http://www.ehow.com/how_4490747_fix-unable-initialize-vse-engine.html" rel="ugc">http://www.ehow.com/how_4490747_fix-unable-initialize-vse-engine.html</a><br />
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Here's better info, because to reinstall Notes entirely seems rather a crude solution:<br />
<a href="http://www-01.ibm.com/support/docview.wss?uid=swg21180665" rel="ugc nofollow">http://www-01.ibm.com/support/docview.wss?uid=swg21180665</a>
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You should have mentioned your source: http://www.ehow.com/how_4490747_fix-unable-initialize-vse-engine.html [http://www.ehow.com/how_4490747_fix-unable-initialize-vse-engine.html]

Here's better info, because to reinstall Notes entirely seems rather a crude solution:
http://www-01.ibm.com/support/docview.wss?uid=swg21180665 [http://www-01.ibm.com/support/docview.wss?uid=swg21180665]

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I have a Windows XP user on a IBM T42 laptop who is trying to launch local install of Lotes Notes 8.0.2, and she's receiving the following error message: Error: Unable to initialise the VSE Engin. &nbsp;User has rebooted twice. &nbsp;No problems were reported before today. &nbsp;No Notes processes were locked up prior to starting. &nbsp;User did say something about she was not able to open Notes while on the VPN yesterday.
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I have a Windows XP user on a IBM T42 laptop who is trying to launch local install of Lotes Notes 8.0.2, and she's receiving the following error message: Error: Unable to initialise the VSE Engin.  User has rebooted twice.  No problems were reported before today.  No Notes processes were locked up prior to starting.  User did say something about she was not able to open Notes while on the VPN yesterday.

Lotus Notes 8.0.2 error message when Notes is initailly launched

Lotus Software produced the Lotus 1-2-3 spreadsheet program, and later developed Lotus Notes, a groupware and email system. Following its acquisition by IBM, the Notes and Domino client/server collaborative platform were expanded to include functions such as email, calendars, to-do lists, contacts management, teamrooms, discussion forums, file sharing, microblogging, instant messaging, blogs, and user directories. IBM also release SmartSuite, a comprehensive office suite, and followed that with Symphony, unrelated to the Lotus suite of the same name.