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VB.net Windows Application - Access MSSQL Server Database that is located on a webserver

Last Modified: 2012-05-08
I have developed a Vb.net Windows application and now i want to put it's database, which is on  MSSQL Express 2005, on a web server so that multiple users from multiple locations can access and update it simultaneously.
How can i do that? What security issues might arise?
Is there another way to implement this?  e.g. VPN (with VPN though can i constraint the users to only access the database)
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