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Allow domain user COM port changes

Hello,
      I am supporting a testing lab for power plant equipment and the management are restricting the domain user account from being in the local administrator account on the testing systems.
Using various SysInternals tools, permissions issues are being resolved except for the issue of the ability to change COM Port settings is required for certain tests.
How do I provide a domain user the ability to change COM Port settings without making them the local administrator?
The systems are in a Windows 2003 Active Directory domain.
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lamaslany
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What kind of settings do they need to be able to change?
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Baud rate, flow control, etc.
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lamaslany
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PS:  If you are using 64-bit versions of Windows Server 2003 you will need to grant permissions to the following key too:

HKEY_LOCAL_MACHINE\SOFTWARE\Wow6432Node\Microsoft\Windows NT\CurrentVersion\Ports
lamaslany,
    I will test that option and get back to you. I should be able to do that within the next business day or two.
Greg
Lamaslany,
       The permissions applied to the key via GPO appeared to work as desired. Of course, they have another application that, no matter what I've tried using Sysinternals Process Monitor and attempting to track down the registry entries and folders, the legacy application keeps prompting that the app has to be run by an Administrator.
I will go ahead and award the points and the original question was answered successfully for the COM port changes via Device Manager.
Thanks!