I have two XP Pcs that have suddenly developed this problem. it's happening for all applications. If I click on ,lets say a pdf, nothing happens for about 45 seconds, then the PDF will open. This happens for local PC documents as well as those on network shares. If I open Adobe Reader first and then open the pdf, it opens instantly. Nothing has changed on these two PCs, no updates, new hardware or software, nothing. If I disable the network connection, program and document load instantly. I have noticed also that in Tools ..Folder Options, if I click the File Types tab the 'searchlight' takes about 45 seconds to display the file associations. All of the Associations are correct, and the DDE options are the same on these PCs as on the working PCs.