550 #5.1.0 Address rejected

I am getting some bounces from an application that is not hosted at my site.  An email is generated at the login phase.  We are attempting to relay it from the hosting service and I fear that this may be a problem for some spam filters.  I have sent test messages directly from myself and they are being delivered.  

Is there a way to safely relay an email message such as this and not be caught in the spam filters?

Listed below is part of the message received.

Received: from enterprise.filter (localhost.localdomain [])      by
 oc-smtp1.mxpath.net (MXPath Final Delivery) with SMTP id AE3DC33698      for
 <mhmg.cjarmon@med.nyu.edu>; Thu,  1 Apr 2010 15:16:18 +0000 (GMT)
Received: from AAAHC-MAIL-ET.AAAHC.org (unknown [])
      (using TLSv1 with cipher AES128-SHA (128/128 bits))
      (No client certificate requested)
      by oc-smtp1.mxpath.net (MXPath Final Delivery) with ESMTP id 41E612BC21
      for <mhmg.cjarmon@med.nyu.edu>; Thu,  1 Apr 2010 15:16:18 +0000 (GMT)
Received: from DEDR62 ( by BreakTechRelay.aaahc.org (
 with Microsoft SMTP Server id; Thu, 1 Apr 2010 10:15:35 -0500
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I think the message is being rejected as it does not come from a registered domain. Supposed your registered mail domain is xyz.com and you are trying to send from abc@app.xyz.com, then problem arises when the recipient's email filter checks for reverse dns (meaning app.xyz.com is not registered) and it rejects it as it thinks it is spam. You need to configure the application to send from abc@xyz.com and it should go fine.

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