Why I can't upload Multiple Documents?

I get this error when attempting to use "Upload Multiple Documents" from within a Document Library.

(I am able to reach the Upload Document page, and interface with the explorer view, but when I choose my files and click OK, it seems that SharePoint is about to upload the files but it stops with this error)
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Shailaja KumarCommented:
Have you modified or customized the upload.aspx file in the 12 hive directly, as this is a known issue with the customised upload.aspx. If yes, then follow the resolution in the below link,

if not, then, go to central administration, Application management, select the web application that is causing the error, Turn off Enable Client Integration. This should be fixing the issue

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there is a limitation whenyou upload Multiple Documents , to solve this use the link to download a tool to upload Multiple Documents without limit
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