Best way to send mass emails with Coldfusion 9 and MySQL

I need to send about 50k+ emails out to my members twice a day. Im trying to find out the best way to do this, Should I use CFmail, if so how? Note: I'm sending a HTML formatted email blast. I'm using a MySQL database.
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overcolorAuthor Commented:
Thank you javasharp but what coding should I use?
Use CFMAIL to send mail. If you want to extract the data from MySQL, use CFQUERY tag.

overcolorAuthor Commented:
Can coldfusion send 50k + emails?
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