I have a system that will not run exe files when logged into one user account. The other two accounts that are used will run the files. When logged into one of the other functional accounts I tried to access the user account from the "Documents and Settings" and the system states the "Access is Denied". When I initially received the system, I ran Malware Bytes and it cleaned multiple files/registry entries. When I try to execute an "exe" file the "Open With" window appears. This occurs in "Safe Mode with Networking" as well as the standard boot. MalewareBytes appeared to clean the "Cleanup Antivirus".
What should I try next?