WSUS Unable to Download Updates

Hi,
Unable to download Microsoft Update from Server, When ever we try to approve
any update on the WSUS, we are getting the following error message.

Error: "The files for this update failed to download. the update can be
approved but will not be available to computers
until the download is complete"

In Event Viewer I'm getting an error 364
Event Type:      Error
Event Source:      Windows Server Update Services
Event Category:      Synchronization
Event ID:      364
Date:            4/13/2010
Time:            11:03:36 AM
User:            N/A
Computer:      NEXFILEB
Description:
Content file download failed. Reason: Error calling [kernel32.dll]:CreateDirectory(e:\wsus\wsuscontent\WsusContent\B1) Source File:  Destination File: .

For more information, see Help and Support Center at http://go.microsoft.com/fwlink/events.asp.

I tried the link http://support.microsoft.com/?kbid=922330 but when I run the command it shows I get an error that it can't find the directory.  Any help is greatly appreciated