I have Exchange 2010 with Outlook anywhere enabled. My enviornment consists of laptops off my domain so I'm using outlook anywhere to conect via http to my echange server. Everything connects up in Outlook 2007 and Exhchange shows online but when I try to send emails to another exchange account I get. "The Connection to MS Exchange is unavailable. Outlook must be online or connected to complete this task."
The interesting thing is I'm able to send to ceratin accounts in exchange that I've sent to befor setting up Outlook anywhere. Also get the Offline error when trying to access the global address book in Exchange.
It's got to be an address book issue.. right? The laptops I setup on my domain and then moved off site work fine. It's the new off-site systems that are having the issue.