I don't have much experience with dual monitors. I just set up a system as follows:
PC with an nVidia GT9800 card
Dell 24" LCD on the HDMI port - monitor #1
Older Samsung Plasma TV on the DVI port (no HDMI input) - monitor #2
It works great, but I have an issue when I have a web based streaming video (Netflix, Hulu, etc.) running in full screen mode on the plama (monitor #2), and then click on anything on Monitor number one, it kicks the video on monitor #2 back down to normal size. It is annoying when I am watching a show an trying to get some work done. Is there a way to tell monitor #2 to ignore what is happening on monitor #1 so the browser stays in full screen mode?