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Outlook 2007 problems connecting to Exchange 2007 Server

Digbert91
Digbert91 asked
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Last Modified: 2012-05-09
Win 2003 Server DC and Exchange 2007 servers were rebooted last night after updates.
Exchange 2007 update rollup 10 was installed. Most users this morning have had to supply a username and password to the dialogue box to login to the Exchange server again via Outlook 2007 using domian\username. Two users out of 100 cannot connect at all using Outlook 2007. Webmail for the users is working fine.

I have tried changing passwords, remove outlook profile (but cannot connect to server to reinstate) taking off domain and then adding them again. Tried another PC, same issue.
"The connection to Microsoft Exchange is unavailable"

On the same AD domain, can ping ping both DC and Mail server

More worringly I've just tried to add a new user and we are getting the same message
"The connection to Microsoft Exchange is unavailable"
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