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Microsoft Office Access can't open the database because it is missing, or opened exclusively by another user

I get this error when I try to open an access database and run a macro from vb.net: "Microsoft Office Access can't open the database because it is missing, or opened exclusively by another user."

I have searched high and low for a solution.  It went away for a few times, now it is back and I have no idea why.  My research tells me it might be a security issue on the server, though I get the error whether I run it on a local datbase or a network database.  Any ideas?
RunPickAccessMacro ("test")
Private Sub RunPickAccessMacro(ByVal sMacro As String)
        Dim oAccess As Access.ApplicationClass
            oAccess = CreateObject("Access.Application")
            oAccess.Visible = True
            oAccess.UserControl = True
            oAccess.AutomationSecurity = 1
            'oAccess.OpenCurrentDatabase("\\mwwnas1\mwwnas1f\mis\Projects_Prod\PickTick\pickticket97_test2.mdb;", False, False)
            oAccess.OpenCurrentDatabase("c:\test.mdb;", False, False)

            'Clean-up: Quit Access without saving changes to the database.
            oAccess = Nothing

        Catch ex As Exception
            sErrNo = Err.Number.ToString
            sError = "**Macro" & vbCrLf & Err.Description & " " & "ErrNo: " & sErrNo
        End Try
    End Sub

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2 Solutions
I would suggest downloading Process Explorer from MS/sysinternals, http://technet.microsoft.com/en-us/sysinternals/bb896653.aspx which you can use to see which process(es) have a handle open for a particular file.  When you encounter this error again, run ProcessExplorer.exe and use Ctrl+F to search for your database name (test.mdb). It should find the process that is currently accessing the file.  I would guess it is an AV product, but this will show you for sure.  

Once you identify the process that is has the file open, shut that other process down, or put in exclusions for your database if it is an AV or HIPS product.
Have you tried opening the database passively instead of with strict permissions?  
Delta7428Author Commented:
yes, I added permissions hoping it might help.
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