We are having a problem where when you open "My Computer" it takes forever to populate the first time, subsiquesnts are fine. If you leave for a while and come back it may or may not happen again. Kind of like it's waiting for something. We have 2 drives mapped to the UK, if we disconnect them the problem goes away. This does not happen to everyone, and it seems if you create a net profile for the user that fixes it as well, at least for the short term. We also have a problem where runas takes just as long to come up and ask for credentials. I think they are linked, and I think it has something to do with the AD and maybe replication?