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Also the Windows Firewall on both TMG boxes is turned off. 
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Also the Windows Firewall on both TMG boxes is turned off.

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Ok so I have narrowed it down to being TMG itself that is causing the block. I uninstalled it from one of my TMG servers and can now access it. <br />
<br />
My problem is I don't know what to change in TMG to allow ping and RDP to these servers as I have it installed and working fine in my lab. 
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Ok so I have narrowed it down to being TMG itself that is causing the block. I uninstalled it from one of my TMG servers and can now access it.

My problem is I don't know what to change in TMG to allow ping and RDP to these servers as I have it installed and working fine in my lab.

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Hi,<br />
<br />
I recently installed TMG on 2 servers (Array) running server 2008 R2. I was able to connect to them fine from anywhere but since running the security wizard on #1 and then copying that xml file to #2 I have been unable to connect to them from most machine. When I say most Im able to RDP and ping both machine from my laptop, however no one else can and not even the 2 servers can talk to each other. <br />
<br />
I have rolled the security profiles back to the orginals and played with the TMG rules and policies with no luck. <br />
<br />
Any help would be appreciated. 
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Hi,

I recently installed TMG on 2 servers (Array) running server 2008 R2. I was able to connect to them fine from anywhere but since running the security wizard on #1 and then copying that xml file to #2 I have been unable to connect to them from most machine. When I say most Im able to RDP and ping both machine from my laptop, however no one else can and not even the 2 servers can talk to each other. 

I have rolled the security profiles back to the orginals and played with the TMG rules and policies with no luck. 

Any help would be appreciated. 

Connection problems to my TMG boxes.

The Microsoft Server topic includes all of the legacy versions of the operating system, including the Windows NT 3.1, NT 3.5, NT 4.0 and Windows 2000 and Windows Home Server versions.

Microsoft Server OS

Microsoft Forefront, formerly known as Internet Security and Acceleration Server (ISA Server), is a network router, firewall, antivirus program, VPN server and web cache that runs on Windows servers. It includes identity management and protection systems, and discontinued systems for threat management and network protection, along with protection for Sharepoint and Exchange. The scope of discussions includes forward and reverse proxy, application and service publishing, virtual private networks (VPNs), outbound access rules, SSL certificates and network routing within either a single node or an highly-available array pairing.