Cannot Delete Datastore using vClient ESXi 4.1

Receive this error message Call "HostDatastoreSystem.RemoveDatastore" for object "ha-datastoresystem" on ESXi "192.168.x.x" failed when deleting the datastore. Please help.
BMRTAsked:
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rsg_itConnect With a Mentor Commented:
I recently needed to migrate a number of VMs using vMotion in order to increase the Block Size of the local datastore of my ESXi host.  After migrating them, I had this error while trying to delete the datastore in advance of changing the block size.  Removing the VMs from inventory - even though they were now functioning from a diiferent datastore - allowed me to delete the original datastore and add it back with the new Block Size.

Thanks to ryder0707 for the hint!  http://www.experts-exchange.com/Software/VMWare/Q_24675379.html
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CCI_ITCommented:
There is a VM using one of the files on that datastore. probably a cd image still in use by a VM on that host.
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