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The server method 'SetObject' failed

Exchange 2010 enterprise single server with multiple roles is giving error (attached) while saving any options under setting page of OWA.

ECP & OWA on EMC are configured for form authentication.  On IIS both ECP & OWA Virtual directories are having anonymous and basic authentication set. I want to save signature and font size and am unable to do so due to this.    User generated image
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Jdtuck
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I have already checked that post. It doesn't helps me. Could you please give a concern?
So the /ecp virtual dierectory has anonymous permissions?  You can also change the domain binding to include a preceding www instead of https://domain.com/owa how about  https://www.domain.com/owa?
anonymous logon is having read & execute permission on ECP virtual directory security tab. No luck after changing any bindings on ecp directory.

even remove and create a new ecp directory.
Can someone respond on this please?
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