Where do I block process names from launching in local group policy

Where do I block process names from launching in local group policy?  Some of our users keep wandering into regedit and messing around with settings.
Thanks,
         Jason
CPUAffinityAsked:
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Emredrum76Commented:
HOW TO: Restrict Users from Running Specific Windows Programs in Windows 2000 - http://support.microsoft.com/kb/323525

“Prevent Access to Registry Editing Tools” policy changes in  Windows XP and in Windows Server 2003 - http://support.microsoft.com/kb/831787

One approach is a GP the other is Registry based.

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