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If you us this code, it will work for you:<br />
<br />
<br />
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<pre><code class="code-1 nolinks" id="code-1280139"><span>if e.columnindex = Directcast(sender, DataGridView).Columns.IndexOf(&quot;columnname&quot;))</span>
</code></pre>
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Sorry had too many ) and omitted then and end if-- see revised code here:<br />
<br />

<pre><code class="code-1 nolinks" id="code-1280185"><span>If e.ColumnIndex = DirectCast(sender, DataGridView).Columns.IndexOf(&quot;columnname&quot;) Then</span>
<span>....</span>
<span>End If</span>
</code></pre>
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rogerard, in this part of code an error appear:<br />
<br />
IndexOf(&quot;columnname&quot;) -&gt; value of type string cannot be converted to system.windows.forms.datag<wbr />ridviewcol<wbr />umn
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Sorry. &nbsp;Try this:<br />
<br />
<br />
<br />

<pre><code class="code-1 nolinks" id="code-1280277"><span>If e.ColumnIndex = DirectCast(sender, DataGridView).Columns.IndexOf(DirectCast(sender, DataGridView).Columns.Item(&quot;columnname&quot;)) Then</span>
<span>....</span>
<span>    End If</span>
</code></pre>
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Or simpler, this:<br />
<br />

<pre><code class="code-1 nolinks" id="code-1280283"><span>    If e.ColumnIndex = DirectCast(sender, DataGridView).Columns.Item(&quot;columnname&quot;).Index Then</span>
<span>....</span>
<span>    End If</span>
</code></pre>
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<div class="content wysiwyg-content">
 Private Sub DgvDetalhe_CellClick(ByVal<wbr /> sender As Object, ByVal e As System.Windows.Forms.DataG<wbr />ridViewCel<wbr />lEventArgs<wbr />) Handles DgvDetalhe.CellClick<br />
<br />
If e.ColumnIndex = 2 Then<br />
&nbsp;.......<br />
endif<br />
<br />
Is possible replace column index by column name, something like if e.columnindex=&quot;column1&quot; then
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 Private Sub DgvDetalhe_CellClick(ByVal sender As Object, ByVal e As System.Windows.Forms.DataGridViewCellEventArgs) Handles DgvDetalhe.CellClick

If e.ColumnIndex = 2 Then
 .......
endif

Is possible replace column index by column name, something like if e.columnindex="column1" then

vb.net datagridview column name

Visual Basic .NET (VB.NET) is an object-oriented programming language implemented on the .NET framework, but also supported on other platforms such as Mono and Silverlight. Microsoft launched VB.NET as the successor to the Visual Basic language. Though it is similar in syntax to  Visual Basic pre-2002, it is not the same technology,